CVM

CVM is an archive format used in the PS2 versions of Persona 3 and Persona 4. It was developed by CRI Middleware and based on ISO9660. Essentially, they are ISO files with a special header. All game data (except the executable) is stored in CVM archives.

cvm_tool.exe
Commandline tool ROFS tool v0.02 was released by roxfan in 2010. It can "split" the CVM into separate header and ISO files, so that you can edit the contents of the archive and then "make" a new CVM. The tool can be found in TGE's PersonaPatcher. For more information on editing ISO files, see ISO.

DKZStudio
DKZ is the only currently known program that can edit CVM files directly. The latest available version is 0.92 Beta. It was originally released in Spanish, but has support for Language packs in DSL format. An English language DSL is included in the download. However, there are some limitations to be aware of. All changes to a CVM are saved automatically, and using the program's built-in "save" function seems to be broken. You also cannot replace small files with bigger ones without corrupting the CVM.